5-Amino-1MQ 10mg – NNMT Inhibitor

Description

5-Amino-1MQ 10mg is a small-molecule compound investigated for its inhibitory activity against nicotinamide N-methyltransferase (NNMT). Available from Pep Lab London, this 10mg material is intended for controlled biochemical investigations involving enzyme activity, nicotinamide metabolism and cellular signalling pathways.

Supplied exclusively for non-clinical laboratory research. Not for human or veterinary use.

What Is 5-Amino-1MQ?

5-amino-1-methylquinolinium is a synthetic quinolinium compound studied as an inhibitor of NNMT, an enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide.

This enzyme participates in cellular methylation processes and nicotinamide metabolism, making it a subject of experimental biochemical research.

The compound has been investigated in enzyme assays, cultured-cell experiments and preclinical animal models. It is a small molecule, not a peptide.

5-Amino-1MQ 10mg – Technical Specifications

• Product: 5-Amino-1MQ
• Quantity: 10mg
• Chemical name: 5-amino-1-methylquinolinium
• Compound type: Small-molecule NNMT inhibitor
• Chemical class: Quinolinium compound
• Molecular formula (cation): C₁₀H₁₁N₂⁺
• Molecular weight (cation): 159.21 g/mol
• CAS number (cation): 685079-15-6
• Physical form: Solid research material
• Supplied salt form: Refer to batch documentation
• Intended application: In-vitro laboratory investigation

Technical note: The formula, molecular weight and CAS number above describe the quinolinium cation. The supplied salt may have a different formula and molecular weight. Refer to the applicable Certificate of Analysis for batch-specific identification.

NNMT Inhibition and Biochemical Pathways

Nicotinamide N-methyltransferase is involved in the conversion of nicotinamide to 1-methylnicotinamide (1-MNA). This reaction forms part of a wider network of cellular methylation and metabolic processes.

Published preclinical studies have investigated how small-molecule NNMT inhibitors affect enzyme activity and associated biochemical markers under controlled experimental conditions.

Experimental observations depend on the biological model, compound concentration and assay methodology. These findings do not establish human clinical safety or efficacy.

5-Amino-1MQ Research Applications

Investigations involving this compound include:

• Enzyme inhibition assays: Measurement of NNMT activity and inhibition in controlled biochemical systems.
• Nicotinamide metabolism: Examination of metabolic processes involving nicotinamide and 1-MNA.
• NAD+ pathway analysis: Investigation of relationships between nicotinamide metabolism and cellular NAD+ pathways.
• Cellular biochemical studies: Measurement of experimental changes in cultured-cell models.
• Small-molecule characterisation: Examination of compound properties and experimental assay responses.

Published Scientific References

Independent scientific publications describe the investigation of NNMT inhibitors in laboratory and preclinical models.

• PubMed – Small-Molecule NNMT Inhibitor Study (2018)
• PubMed – NNMT Inhibition and Mouse Microbiome Research (2022)

Both publications relate to preclinical research. Results from these studies should not be interpreted as evidence of therapeutic benefits in humans.

Quality Information and Certificate of Analysis

Technical documentation is an important consideration when sourcing small-molecule materials for laboratory investigations.

Researchers should review the relevant batch Certificate of Analysis (COA), including available information about chemical identity, purity, supplied salt form and analytical testing.

Contact Pep Lab London for available batch-specific quality documentation.

Laboratory Handling and Storage

Handle this material using appropriate laboratory protective equipment and established chemical safety procedures.

Refer to supplier documentation and the applicable Safety Data Sheet for validated storage conditions, solvent compatibility and stability information.

Follow institutional standard operating procedures when working with experimental materials.

Related Products at Pep Lab London

Customers looking for a different vial quantity or related biochemical materials can explore:

• 5-Amino-1MQ 50mg – Alternative Vial Quantity
• Metabolic Research Materials
• Cellular Research Materials

Individual products have different chemical characteristics and should be evaluated separately for their intended experimental applications.

About Pep Lab London

Pep Lab London is a UK-based supplier of laboratory and scientific research materials.

Customers can explore product specifications, compare available vial quantities and request supporting batch documentation.

Research Use Only – Important Safety Notice

5-Amino-1MQ 10mg is supplied exclusively for laboratory research and controlled scientific investigation.

It is not intended for human consumption, human or veterinary administration, medical treatment, diagnosis, supplementation or cosmetic use.

Purchasers must ensure that the acquisition, storage, handling and use of this compound comply with applicable regulations and institutional requirements.